Abantu icumi ba mbere muri kamere mubumenyi:

Yunlong Cao wo muri kaminuza ya Peking yitiriwe ubushakashatsi bushya bwa coronavirus

Ku ya 15 Ukuboza 2022, Kamere yatangaje 10 ya Kamere yayo, urutonde rwabantu icumi bagize uruhare mu bikorwa by’ubumenyi by’umwaka, kandi inkuru zabo zitanga icyerekezo cyihariye kuri bimwe mu bintu bya siyansi by’ingenzi byabaye muri uyu mwaka udasanzwe.

Mu mwaka w’ibibazo no kuvumbura gushimishije, Kamere yahisemo abantu icumi mu bumenyi bw’inyenyeri badufashe gusobanukirwa n’ikirere kiri kure cyane, kugeza ku bashakashatsi bagize uruhare runini mu byorezo bishya bya Crown na monkeypox, kubaga babaga barenze imipaka yo guhinduranya ingingo. , nk'uko byatangajwe na Rich Monastersky, umwanditsi mukuru w'ibidukikije.

Yunlong Cao akomoka muri Biomedical Frontier Innovation Centre (BIOPIC) muri kaminuza ya Peking. Dr. Cao yarangije muri kaminuza ya Zhejiang afite impamyabumenyi ya Bachelor muri Physique kandi yakuye impamyabumenyi y'ikirenga ya PhD mu ishami rya kaminuza ya Harvard ishami ry’ubutabire n’ubumenyi bw’ibinyabuzima iyobowe na Xiaoliang Xie, ubu akaba ari umunyeshuri w’ubushakashatsi mu kigo cya Biomedical Frontier Innovation Centre muri kaminuza ya Peking. Yunlong Cao yibanze cyane ku iterambere rya tekinoroji ikurikirana imwe, kandi ubushakashatsi bwe bwafashije gukurikirana ihindagurika rya coronavirus nshya no guhanura zimwe mu ihinduka ry’imihindagurikire itera ihinduka ry’imiterere mishya.

Ku ya 18 Gicurasi 2020, Xiaoliang Xie / Yunlong Cao n'abandi. yasohoye urupapuro mu kinyamakuru Cell yise: "Imbaraga zangiza antibodiyite zirwanya SARS-CoV-2 zagaragajwe n’urwego rwinshi rukurikirana ingirabuzimafatizo imwe y’ingirabuzimafatizo za B".

Ubu bushakashatsi butangaza ibyavuye muri coronavirus nshya (SARS-CoV-2) itesha agaciro ecran ya antibody, yakoresheje uburyo bwinshi bwo kwinjiza ingirabuzimafatizo imwe ya RNA na VDJ kugira ngo hamenyekane antibodiyite 14 zangiza cyane za antibodiyite zirenga 8500 zirwanya antigen. 60 bakize abarwayi ba COVID-19.

Ubu bushakashatsi bwerekana ku nshuro ya mbere ko urwego rwinshi rwinjira mu ngirabuzimafatizo imwe rukumbi rushobora gukoreshwa mu buryo butaziguye mu kuvumbura ibiyobyabwenge kandi bifite inyungu zo kuba inzira yihuse kandi ifatika, isezeranya guhindura uburyo abantu bagaragaza kugira ngo babuze antibodi virusi zanduye.

Ku ya 17 Kamena 2022, Xiaoliang Xie / Yunlong Cao n'abandi. yasohoye urupapuro rwiswe: BA.2.12.1, BA.4 na BA.5 guhunga antibodi zatewe n'indwara ya Omicron mu kinyamakuru Nature.

Ubu bushakashatsi bwerekanye ko ubwoko bushya bw’imiterere ya Omicron mutant BA.2.12.1, BA.4 na BA.5 bwerekanye ko ubudahangarwa bw’umubiri bwiyongera ndetse no kutabogama gukabije kwa plasma ku barwayi banduye Omicron BA.1.

Ibyavuye mu bushakashatsi byerekana ko urukingo rwa BA.1 rushingiye ku rukingo rwa Omicron rushobora kuba rutagikwiriye kuba urwego rwo gukingira ubu kandi ko antibodies zatewe zitazatanga uburinzi bwagutse bwo kwirinda indwara nshya. Byongeye kandi, ubudahangarwa bw’amatungo binyuze mu kwandura Omicron biragoye cyane kubigeraho bitewe n’ikibazo cya 'immunogenic' cya coronavirus nshya ndetse n’ihindagurika ryihuse ry’imiterere y’imiterere y’imiterere.

Ku ya 30 Ukwakira 2022, itsinda rya Xiaoliang Xie / Yunlong Cao ryasohoye inyandiko y’ubushakashatsi yise: Imprinted SARS-CoV-2 ubudahangarwa bw’urwenya butera ubwihindurize bwa Omicron RBD mu ntangiriro ya bioRxiv.

Ubu bushakashatsi bwerekana ko ibyiza bya XBB kurenza BQ.1 bishobora guterwa nimpinduka ziva hanze ya reseptor ihuza domaine (RBD) ya spinosine, ko XBB ifite kandi ihinduka mubice bya genome ikubiyemo N-terminal yubatswe (NTD) ) ya spinosine, kandi ko XBB ibasha guhunga kutabuza antibodiyite kurwanya NTD, ishobora kwemerera kwanduza abantu ubudahangarwa bwa BQ.1 hamwe nubwoko bujyanye nayo. Ariko, birakwiye ko tumenya ko ihinduka ryimiterere mukarere ka NTD ribera muri BQ.1 kumuvuduko mwinshi cyane. Ihinduka ryongera cyane ubushobozi bwizo variants zo guhunga antibodiyite zidafite aho zibogamiye zatewe ninkingo nindwara zabanje.

Dr. Yunlong Cao yavuze ko hashobora kubaho uburinzi kuri XBB iyo bwanduye BQ.1, ariko hakenewe ubundi bushakashatsi kugira ngo butange ibimenyetso kuri ibi.

Usibye Yunlong Cao, abandi bantu babiri bakoze urutonde kubera uruhare runini bagize mu bibazo by’ubuzima rusange ku isi, Lisa McCorkell na Dimie Ogoina.

Lisa McCorkell ni umushakashatsi ufite Long COVID kandi nkumunyamuryango washinze ubushakashatsi bw’abarwayi bayobowe n’ubushakashatsi, yafashije mu gukangurira no gutera inkunga ubushakashatsi ku ndwara.

Dimie Ogoina ni umuganga w’indwara zandura muri kaminuza ya Delta ya Nigeriya muri Nijeriya kandi ibikorwa bye ku cyorezo cya monkeypox muri Nijeriya byatanze amakuru y'ingenzi mu kurwanya icyorezo cya monkeypox.

Ku ya 10 Mutarama 2022, Ishuri Rikuru ry’Ubuvuzi rya kaminuza ya Maryland ryatangaje ko ku nshuro ya mbere isi yatsindiye umutima w’ingurube yatewe mu muntu muzima, ubwo umurwayi w’umutima David Bennett w’imyaka 57 yakiraga ingirabuzima fatizo y’umutima w’ingurube kugira ngo arokore ubuzima bwe. .

Nubwo uyu mutima wingurube wongereye ubuzima bwa David Bennett amezi abiri gusa, byabaye intsinzi nini niterambere ryamateka mubijyanye na xenotransplantation. Muhammad Mohiuddin, umuganga ubaga wayoboye itsinda ryasoje iyi transplant ya muntu y’umutima w’ingurube wahinduwe na genetike, nta gushidikanya ko yashyizwe ku rutonde rw’abantu 10 ba mbere b’ibidukikije.

Abandi benshi batoranijwe kugira ngo bateze imbere ubumenyi budasanzwe mu bya siyansi ndetse no mu iterambere ry’ingenzi muri politiki, barimo umuhanga mu bumenyi bw'ikirere Jane Rigby wo mu kigo cya Goddard Space Centre cya NASA, wagize uruhare runini mu butumwa bwa Webb Space Telescope bwo kugeza telesikope mu kirere no gukora neza, bifata ubushobozi bw'abantu bwo gushakisha isanzure kugeza kurwego rushya kandi rwisumbuye. alondra Nelson, nk'umuyobozi w’agateganyo wa politiki y’ubumenyi n’ikoranabuhanga muri Amerika mu biro by’ubumenyi n’ikoranabuhanga, yafashije ubuyobozi bwa Perezida Biden guteza imbere ibintu byingenzi bigize gahunda y’ubumenyi, harimo politiki y’ubusugire bwa siyansi n’amabwiriza mashya yerekeye siyanse ifunguye. Diana Greene Foster, umushakashatsi ukuramo inda akaba n'umu demografiya muri kaminuza ya Californiya, San Francisco, yatanze amakuru y'ingenzi ku ngaruka ziteganijwe ku cyemezo cy'Urukiko rw'Ikirenga rwo muri Amerika cyo gukuraho uburenganzira bwo gukuramo inda.

Hariho kandi amazina kurutonde icumi rwambere rwuyu mwaka rufite akamaro mu iterambere ry’imihindagurikire y’ikirere n’ibindi bibazo by’isi yose. Abo ni: António Guterres, umunyamabanga mukuru w’umuryango w’abibumbye, Saleemul Huq, umuyobozi w’ikigo mpuzamahanga gishinzwe imihindagurikire y’ikirere n’iterambere i Dhaka, muri Bangladesh, na Svitlana Krakovska, umuyobozi w’intumwa za Ukraine mu kanama gashinzwe umutekano ku isi (UN). IPCC).