Abarwayi ba kanseri y'ibihaha, kwipimisha MRD birakenewe?

MRD (Minimal Residual Disease), cyangwa Minimal Residual Disease, ni umubare muto w'uturemangingo twa kanseri (selile kanseri ititabira cyangwa irwanya imiti) iguma mu mubiri nyuma yo kuvura kanseri.
MRD irashobora gukoreshwa nka biomarker, hamwe nigisubizo cyiza bivuze ko ibikomere bisigaye bishobora kugaragara nyuma yo kuvura kanseri (kanseri ya kanseri iboneka, kandi kanseri ya kanseri isigaye irashobora gukora kandi igatangira kwiyongera nyuma yo kuvura kanseri, bigatuma isubiramo rya indwara), mugihe ibisubizo bibi bivuze ko ibikomere bisigaye bitamenyekana nyuma yo kuvura kanseri (nta selile ya kanseri iboneka);
Birazwi neza ko kwipimisha MRD bigira uruhare runini mu kumenya abarwayi bo mu cyiciro cya mbere kitari gito kanseri y'ibihaha (NSCLC) bafite ibyago byinshi byo kongera kubaho ndetse no kuyobora imiti ivura nyuma yo kubagwa bikabije.
Ibihe bishobora gukoreshwa MRD:

Kuri kanseri y'ibihaha hakiri kare

1. Nyuma yo gukuraho byimazeyo abarwayi ba kanseri y'ibihaha itari mito mito, positivite ya MRD yerekana ibyago byinshi byo kongera kubaho kandi bisaba gukurikiranirwa hafi.Gukurikirana MRD birasabwa buri mezi 3-6;
2. Birasabwa gukora ibizamini byamavuriro ya kanseri yibihaha ya kanseri y'ibihaha idashobora kuba mito ishingiye kuri MRD, kandi igatanga uburyo bwo kuvura neza bishoboka;
3. Saba ubushakashatsi ku ruhare rwa MRD mu bwoko bwombi bw’abarwayi, gene nziza ya shoferi na gene mbi, bitandukanye.

Kuri kanseri y'ibihaha yateye imbere cyane

1.MRD isuzumwa kubarwayi bakira burundu nyuma ya chemoradiotherapie radical ya kanseri y'ibihaha yateye imbere itari mito mito, ishobora gufasha kumenya ibizagerwaho no gushyiraho izindi ngamba zo kuvura;
2. Igeragezwa rya Clinical ya MRD ishingiye ku guhuza imiti nyuma ya chimoradiotherapie irasabwa gutanga uburyo bwiza bwo kuvura uburyo bwo kuvura.
Kuri kanseri y'ibihaha yateye imbere itari nto
1. Habuze ubushakashatsi bujyanye na MRD muri kanseri y'ibihaha yateye imbere itari nto;
2. Birasabwa ko MRD yamenyekana ku barwayi bakira burundu nyuma yo kuvura sisitemu ya kanseri y'ibihaha yateye imbere itari ntoya, ishobora gufasha kumenya ibizagerwaho no gushyiraho izindi ngamba zo kuvura;
3. Birasabwa gukora ubushakashatsi ku ngamba zo kuvura zishingiye kuri MRD ku barwayi bakira neza kugira ngo bongere igihe cyo kuvurwa burundu bishoboka kugira ngo abarwayi bashobore kubona inyungu nyinshi.

Birashobora kugaragara ko kubera kubura ubushakashatsi bujyanye no gutahura MRD muri kanseri y'ibihaha yateye imbere itari ntoya, ikoreshwa rya MRD mu kuvura abarwayi ba kanseri y'ibihaha yateye imbere itari ntoya.
Mu myaka yashize, iterambere mu ntego no gukingira indwara ryahinduye uburyo bwo kuvura abarwayi bafite NSCLC yateye imbere.
Ibimenyetso bigaragara byerekana ko abarwayi bamwe bagera ku kubaho igihe kirekire ndetse bikaba byitezwe ko bazageraho bakira amashusho.Kubera iyo mpamvu, hashingiwe ko amatsinda amwe y’abarwayi bafite NSCLC yateye imbere yagiye atahura buhoro buhoro intego yo kubaho igihe kirekire, gukurikirana indwara zongeye kuba ikibazo cy’amavuriro, kandi niba kwipimisha MRD nabyo bishobora kugira uruhare runini muri byo bikwiye gushakishwa. mubindi bigeragezo byamavuriro.